Do it anyway

Scientists have developed a new mouse model to test how SSRIs work. "Many antidepressants have been shown to target other proteins besides the serotonin transporter and … their efficacy in treating depression takes many weeks to develop." So basically, they still know nothing.

Doctors don't really know how or why the drugs work, they just seem to do something. They're still not really sure about lithium, and it's been used for hysteria for centuries.

The brain is a funny thing? So why do we mess with it? Why pour in fabricated chemical models that we don't know what they do? Why take meds? Because they do work (most of the time), and anything is better than the horrible depression. If you know what I mean, you know why you take meds. Nothing is worse than that black hole, that impermeable fortress of death. Yuck. Yay science!